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Journal: Frontiers in bioscience (Landmark edition)
Article Title: Novel insights into the role of 5-Methylcytosine RNA methylation in human abdominal aortic aneurysm.
doi: 10.52586/5016
Figure Lengend Snippet: Fig. 1. Expression of m5C RNA methylation status (A) and m5C methylation modulators (B, C, D, E, F, and G) at the mRNA level in AAA tissue samples compared with the healthy control aortas analyzed by qRT-PCR. The non-parametric Mann-Whitney U test was all applied to analyze the m5C methylation ratio (A); the m5C “writers” family, NSUN1 (B), NSUN2 (C), NSUN5 (D), NSUN6 (E), Dnmt2 (F); and “readers” family Aly/REF (G). The expression of individual m5C RNA methylation modulators related to the expression of GAPDH set as 1 (100% expression). *, p < 0.05; **, p < 0.01. m5C, 5-Methylcytosine RNA methylation; AAA, abdominal aortic aneurysm; qRT-PCR, quantitative real-time polymerase chain reaction; ns, not significant.
Article Snippet: Then sections were washed 3 times with Tris-buffered saline, and incubated with
Techniques: Expressing, Methylation, Control, Quantitative RT-PCR, MANN-WHITNEY